KR-33028
CAS No. : 861218-37-3
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| Cat. No. : | HY-123659 |
| M.Wt: | 244.27 |
| Formula: | C11H8N4OS |
| Purity: | >98 % |
| Solubility: |
KR-33028 is a selective NHE1 inhibitor. KR-33028 reduces hypoxia-induced necrosis and apoptosis in H9c2 cells. KR-33028 inhibits hypoxia-induced increases in cytoplasmic and mitochondrial Ca2+ levels and cytochrome c release. KR-33028 improves cardiac contractility, reduces lactate dehydrogenase release, and increases tissue ATP, creatine phosphate, and glycogen levels. KR-33028 can be used in research on cancers such as cardioblastoma and cardiovascular diseases such as ischemic stroke[1][2].
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