L 888607
CAS No. : 860033-06-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $320 | In-stock |
| 10mg | $520 | In-stock |
| 25mg | $1100 | In-stock |
| 50mg | $1700 | In-stock |
| 100mg | $2400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-111271 |
| M.Wt: | 375.84 |
| Formula: | C19H15ClFNO2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].
IC50 & Target:Ki: 4 nM (human CRTH2 receptor)[1]
EC50: 0.4 nM(recombinant and endogenously expressed CRTH2 receptor)[1]
In Vitro:L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM[1].
L 888607 has some affinity for the human DP receptor with a Ki value of 211 nM[1].
L 888607 displays a relatively high selectivity for CRTH2 receptor[1].
L 888607 has agonistic activity on recombinant and endogenously expressed CRTH2 receptor with an EC50 value of 0.4 nM[1].
L 888607(100 nM, 20 min) stimulates eosinophil chemotaxis[1].
In Vivo:L 888607 (i.v., 5 mg/kg, single or oral, 20 mg/kg, single) shows relative stability in vivo[1].
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- L 888607
- Cat. No.:
- HY-111271
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