1-Naphthylacetamide


CAS No. : 86-86-2

(Synonyms: NAAM; 1-Naphthaleneacetamide; α-Naphthylacetamide)

86-86-2
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Cat. No. : HY-19699
M.Wt: 185.23
Formula: C12H11NO
Purity: >98 %
Solubility:
Introduction of 86-86-2 :

1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex[1][2]. In Vitro:1-Naphthylacetamide derivatives exhibit significant local anesthetic effects in vitro [1].
1-Naphthylacetamide derivatives (10 μg/mL) exhibit spasmolytic activity in vitro, comparable to the standard agent Atropine (HY-B1205) [1].

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