6-Iodonordihydrocapsaicin
CAS No. : 859171-97-4
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| Cat. No. : | HY-108459 |
| M.Wt: | 419.30 |
| Formula: | C17H26INO3 |
| Purity: | >98 % |
| Solubility: |
6-Iodonordihydrocapsaicin is a TRPV1 antagonist. 6-Iodonordihydrocapsaicin functionally blocks TRPV1-mediated responses, including capsaicin-induced ion currents in dorsal root ganglion neurons and distension-induced firing of jejunal spinal afferent fibers in mice. 6-Iodonordihydrocapsaicin can be used in the research of visceral pain and anxiety disorders[1][2]. In Vitro:6-Iodonordihydrocapsaicin (10 μM) inhibits capsaicin-evoked ionic currents in murine DRG primary cultures[1]. In Vivo:6-Iodonordihydrocapsaicin (1 nmol; intracerebroventricular (i.c.v.); single administration) completely blocks the anxiogenic-like effects of intracerebroventricular Hemopressin (HY-P1090) in male Wistar rats tested in the elevated plus maze[2].
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- 6-Iodonordihydrocapsaicin
- Cat. No.:
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