PSN632408
CAS No. : 857652-30-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $103 | In-stock |
| 10mg | $181 | In-stock |
| 50mg | $744 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-16673 |
| M.Wt: | 360.41 |
| Formula: | C18H24N4O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
PSN632408, a selective, orally active GPR119 agonist, shows similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50=5.6 and 7.9 uM, respectively). PSN632408 can stimulate β-cell replication and improve islet graft function. PSN632408 has the potential for the research of obesity and related metabolic disorders[1][2].
In Vitro: PSN632408 produces concentration-dependent increases in cAMP level with mean EC50 value of 1.9 uM[1].
PSN632408 stimulates β cell replication in cultured mouse islets[2].
In Vivo: PSN632408 (100 mg/kg; p.o.; daily for 14 days) suppresses food intake in rats and reduce body weight gain and white adipose tissue deposition upon subchronic oral administration to high-fat-fed rats[1].
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