Tedizolid
CAS No. : 856866-72-3
(Synonyms: TR 700; Torezolid; DA-7157)
| Size | Price | Stock |
|---|---|---|
| 5mg | $40 | In-stock |
| 10mg | $65 | In-stock |
| 25mg | $110 | In-stock |
| 50mg | $176 | In-stock |
| 100mg | $280 | In-stock |
| 500mg | $700 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-14855 |
| M.Wt: | 370.34 |
| Formula: | C17H15FN6O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic) |
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome. In Vitro: Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP[1]. In Vivo: For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema[1].
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