CEP-14083


CAS No. : 856692-39-2

856692-39-2
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Cat. No. : HY-14243
M.Wt: 518.61
Formula: C31H30N6O2
Purity: >98 %
Solubility:
Introduction of 856692-39-2 :

CEP-14083 is a ATP-competitive ALK kinase inhibitor with an IC50 value in enzymatic assays of 2 nM. CEP-14083 also inhibits other kinases, such as insulin receptor (IR), vascular endothelial growth factor receptor 2 (VEGFR2), angiopoietin-1 receptor (TIE2) and dual leucine zipper kinase (DLK). CEP-14083 suppresses CD274 mRNA expression and the NPM/ALK function in the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells. CEP-14083 is promising for research of lymphoma[1][2].

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