| Size | Price | Stock |
|---|---|---|
| 5mg | $650 | In-stock |
| 10mg | $1050 | In-stock |
| 25mg | $2150 | In-stock |
| 50mg | $3450 | In-stock |
| 100mg | $5400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-115450 |
| M.Wt: | 477.59 |
| Formula: | C29H35NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 220 mg/mL (ultrasonic) |
ONO-0300302 is an orally active and potent LPA1 (lysophosphatidic acid receptor 1) antagonist, with an IC50 of 0.086 μM. ONO-0300302 is a slow tight binding inhibitor, and its binding affinity increases with time, with Kd of 0.34 nM (37 °C, 2 h). ONO-0300302 can be used for benign prostatic hyperplasia (BPH) research[1]. IC50 & Target: IC50: 0.086 μM (LPA1)[1] In Vitro: ONO-0300302 shows moderate stability against rat microsomes[1]. In Vivo: ONO-0300302 inhibits significantly an LPA (lysophosphatidic acid receptor)-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h[1].
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