Curculigoside
CAS No. : 85643-19-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $80 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $330 | In-stock |
| 100mg | $495 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-N0705 |
| M.Wt: | 466.44 |
| Formula: | C22H26O11 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 2 mg/mL |
Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway[1]. IC50 & Target: JAK; STAT; NF-κB[1] In Vitro: Curculigoside (1-64 μg/ml; 72 hours) exerts significant inhibitory effects on MH7A cell viability between 1 and 64 µg/ml in MH7A cells[1]. Curculigoside (4-16 μg/ml; 24 hours) decreases the protein expression of JAK1, JAK3 and STAT3 compared to the TNF-α group[1].
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