Thrombin inhibitor 1
CAS No. : 855998-46-8
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| Cat. No. : | HY-U00370 |
| M.Wt: | 497.32 |
| Formula: | C22H20Cl2F2N4O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM). IC50 & Target: Ki: 0.66 nM (thrombin)[1] In Vitro: Thrombin inhibitor 1 (Compound 4) is binds in the active site of thrombin with Ki of 0.66 nM, 2xaPTT=0.43 uM). Thrombin inhibitor 1 (Compound 4) is evaluated for its thrombin inhibitory potency and its functional ability to double the activated partial thromboplastin time (2xaPTT) in human plasma with a 2xaPTT of 0.43 μM[1].
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