12-Oxo phytodienoic acid
CAS No. : 85551-10-6
(Synonyms: 12-OPDA)
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| Cat. No. : | HY-118828 |
| M.Wt: | 292.41 |
| Formula: | C18H28O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056)-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research[1].
In Vitro:12-Oxo phytodienoic acid (12-OPDA) (7.5, 15, 30 μM, 6, 24 h) protects MG5 cells against inflammation induced by LPS[1].
12-Oxo phytodienoic acid (12-OPDA) (7.5, 15, 30 μM, 6, 24 h) suppresses LPS-induced activation of NF-κB and p38 MAPK and induces SOCS-1 transcription in MG5 cells[1].
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