MB-07811
CAS No. : 852948-13-1
(Synonyms: VK-2809)
| Size | Price | Stock |
|---|---|---|
| 1mg | $114 | In-stock |
| 5mg | $315 | In-stock |
| 10mg | $446 | In-stock |
| 25mg | $760 | In-stock |
| 50mg | $988 | In-stock |
| 100mg | $1437 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-111288 |
| M.Wt: | 514.98 |
| Formula: | C28H32ClO5P |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344, a liver-targeted thyroid hormone receptor-β agonist[1]. MB-07811 has cholesterol and triglycerides lowering activity[2]. IC50 & Target:Thyroid hormone receptor-β[2] In Vitro: MB-07811 (VK-2809) is potential for liver targeting with a low affinity for thyroid hormone receptors (TRβ Ki=14.6 ± 0.5 μM; TRα Ki=12.5 ± 0.6 μM)[2]. In Vivo: MB-07811 (VK-2809) (0.3-30 mg/kg; orally once daily for 14 days) reduces cholesterol and triglycerides in diet-induced obese mice[2].
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