ME-143


CAS No. : 852536-39-1

(Synonyms: NV-143)

852536-39-1
Price and Availability of CAS No. : 852536-39-1
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5mg $270 In-stock
10mg $430 In-stock
25mg $865 In-stock
50mg $1380 In-stock
100mg $2205 In-stock
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Cat. No. : HY-13675
M.Wt: 334.37
Formula: C21H18O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 852536-39-1 :

ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo[1]. IC50 & Target:NADH oxidase[1] In Vitro: ME-143 (0-100 μM; 48 hours) reduces proliferation of DLD1 cell line by approximately 40% at a concentration of 3.125 μM, and is more potent than Genistein[1].

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