Dutogliptin
CAS No. : 852329-66-9
(Synonyms: PHX-1149 (free base))
| Size | Price | Stock |
|---|---|---|
| 1mg | $550 | In-stock |
| 5mg | $980 | In-stock |
| 10mg | $1500 | In-stock |
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| Cat. No. : | HY-10286 |
| M.Wt: | 241.10 |
| Formula: | C10H20BN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 300 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. IC50 & Target: DPP4[1] In Vivo: Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s[2].
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