LJ001


CAS No. : 851305-26-5

851305-26-5
Price and Availability of CAS No. : 851305-26-5
Size Price Stock
5mg $170 In-stock
10mg $270 In-stock
25mg $540 In-stock
50mg $800 In-stock
100mg $1120 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-16957
M.Wt: 327.42
Formula: C17H13NO2S2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 851305-26-5 :

LJ001 is a broad-spectrum and orally active antiviral agent. LJ001 exerts antiviral activities by binding to viral membranes. LJ001 inhibits TGEV and PDCoV infection. LJ001 decreases TGEV N and PDCoV N-protein expression[1][2]. In Vitro:LJ001 (0.782- 200 μM; 24 h) shows no significant cytotoxicity with a CC50 value of 146.4 μM for ST cells[1].
LJ001 (12.5 µM; 12, 24 h) inhibits transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) infection[1].
LJ001 (12.5 µM; 1, 6,12, 24 h) decreases the TGEV and PDCoV gene mRNA expression in ST cells[1].
LJ001 can inhibit the entry and spread of some enveloped viruses, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), influenza, Ebola, arenaviruses and poxvi ruses[1]. In Vivo:LJ001 (20, 50 mg/kg; oral gavage or i.p.; daily for 7 days) shows no toxicity in mouse[2].

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