BX517


CAS No. : 850717-64-5

850717-64-5
Price and Availability of CAS No. : 850717-64-5
Size Price Stock
5mg $80 In-stock
10mg $110 In-stock
25mg $190 In-stock
50mg $350 In-stock
100mg $550 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-13842
M.Wt: 282.30
Formula: C15H14N4O2
Purity: >98 %
Solubility: DMSO : ≥ 27 mg/mL
Introduction of 850717-64-5 :

BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM. IC50 & Target: IC50: 6 nM (PDK1) In Vitro: BX-517 blocks activation of Akt in tumor cells, is potent with IC50 of 0.1-1.0 μM[1]. BX-517 blocks AKT2 activation in cells with submicromolar potency. BX-517 is 100-fold selective or better against a panel of seven additional Ser/Thr and Tyr kinases[2].

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