TG 41
CAS No. : 850339-33-2
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| Cat. No. : | HY-111298 |
| M.Wt: | 440.12 |
| Formula: | C18H13BrCl2N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
TG 41 is positive modulator of GABAA receptor. TG 41 enhances the binding both of GABA and of Flunitrazepam to rat cerebral cortical membranes[1].
In Vitro:TG41 (0.001-10 µM) increases specific [3H]GABA binding to rat cerebral cortical membranes[1].
TG41 (0.001-10 µM) increases inward Cl- currents in X. laevis oocytes expressing recombinant α1β2γ2L GABAA receptors[1].
In Vivo:TG 41 (5 mg/kg, i.v.) elicits hypnosis in rats[1].
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