Fmoc-amino-(PEG)n-acid


CAS No. : 850312-72-0

850312-72-0
Price and Availability of CAS No. : 850312-72-0
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Cat. No. : HY-W019797
M.Wt: 1000.00
Formula: (C2H4O)nC20H21NO5
Purity: >98 %
Solubility:
Introduction of 850312-72-0 :

Fmoc-amino-(PEG)n-acid is a PEG-based PROTAC linker containing an Fmoc-protected amine and a terminal carboxylic acid and can be used in the synthesis of PROTACs. In Vitro:The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

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