m-PEG4-Amine
CAS No. : 85030-56-4
| Size | Price | Stock |
|---|---|---|
| 100mg | $28 | In-stock |
| 250mg | $34 | In-stock |
| 1g | $40 | In-stock |
| 5g | $198 | In-stock |
| 25g | $770 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-W040214 |
| M.Wt: | 207.27 |
| Formula: | C9H21NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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