Rosin
CAS No. : 85026-55-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $165 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-N0508 |
| M.Wt: | 296.32 |
| Formula: | C15H20O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Rosin is a natural oleoresin found in coniferous trees of the genus Pinus, such as Pinus massoniana. Rosin exhibits cholesterol-lowering, anti-gastric ulcer, anti-tumor, blood glucose-lowering, and anti-macrocyte aggregation activities. Rosin inhibits TPA (HY-18739)-induced EBV-EA activation and suppresses papilloma formation in a two-stage mouse skin carcinogenesis model. WBR, a processed product of Rosin, inhibits the IL-23/IL-17 inflammatory axis and reduces Th1 and Th17 cell infiltration. Rosin is used in research on psoriasis and skin cancer[1][2].
In Vitro:Rosin-derived resin acid components inhibit TPA-induced EBV-EA activation in Raji cells[1].
In Vivo:Rosin (50 μg/0.1 mL; topical administration; twice weekly; 20 weeks) exhibits anticancer effects in a two-stage mouse skin carcinogenesis assay[1].
Rosin processed product WBR significantly reduces the proportion of Th17 cells, epidermal thickness, and inflammatory cytokine mRNA expression in the Imiquimod (HY-B0180)-induced psoriasis-like inflammation mouse model[2].
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- Rosin
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