5'-Guanylic acid


CAS No. : 85-32-5

(Synonyms: 5'-GMP; 5'-guanosine monophosphate)

85-32-5
Price and Availability of CAS No. : 85-32-5
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5g $85 In-stock
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Cat. No. : HY-N5134
M.Wt: 363.22
Formula: C10H14N5O8P
Purity: >98 %
Solubility: H2O : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 85-32-5 :

5'-Guanylic acid is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid also causes neuronal cell death at high concentrations[1][2][3]. In Vitro:5'-Guanylic acid (50-500 μM, 48 h) regulates the expression of genes involved in fatty acid metabolism, affects fatty acid composition in Oncorhynchus mykiss hepatocytes, and regulates fatty acid metabolism[1].
In Vivo:5'-Guanylic acid (10-150 mg/kg, ip, single dose) exhibits anti-anxiety effect in Wistar rats models[2].

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