Phenanthrene
CAS No. : 85-01-8
| Size | Price | Stock |
|---|---|---|
| 100g | $17 | In-stock |
| 500g | $78 | In-stock |
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| Cat. No. : | HY-B1727 |
| M.Wt: | 178.23 |
| Formula: | C14H10 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment[1][2][3][4]. In Vitro:Phenanthrene (1-300 μM, 48 h) significantly reduces the mitochondrial membrane potential (MMP) in primary hepatocytes of the Chinese rare minnow (Gobiocypris rarus)[4]. In Vivo:Phenanthrene (180 and 900 mg/kg, p.o., administered once on the first day; 90 and 450 mg/kg, i.p., administered once a day on the next 2 days) induces oxidative stress and inflammation in Wistar female rats[3]. Phenanthrene (10-1000 μg/mL, exposure for 30 days) can cause liver damage and promote hepatocyte apoptosis in Chinese rare minnows (Gobiocypris rarus)[4].
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