Grape seed extract
CAS No. : 84929-27-1
| Size | Price | Stock |
|---|---|---|
| 100mg | $25 | In-stock |
| 250mg | $35 | In-stock |
| 500mg | $45 | In-stock |
| 1g | $60 | In-stock |
| 5g | $99 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
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| Cat. No. : | HY-N7072 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | DMSO : 6 mg/mL (ultrasonic) |
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells[1][2][3].
In Vitro: Grape seed extract (25-100 μg/mL; 12-48 hours) inhibits growth and induces death in human colorectal cancer cells[3].
Grape seed extract (25-100 μg/mL; 12-24 hours) modulates the protein levels of cell cycle regulatory molecules in HT29 and LoVo cells[3].
Grape seed extract (25-100 μg/mL; 24 hours) causes apoptotic cell death of human colorectal cancer cells[3].
In Vivo: Grape seed extract (200 mg/kg; i.g.; 5 days/wk; for 8 weeks) inhibits HT29 colon carcinoma tumor xenograft growth in athymic nude mice[3].
Grape seed extract inhibits cell proliferation but increases apoptotic cell death in tumors[3].
Grape seed extract enhances Cip1/p21protein levels and poly(ADP-ribose) poly-merase cleavage in tumors[3].
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