H4 Receptor antagonist 1


CAS No. : 848217-00-5

848217-00-5
Price and Availability of CAS No. : 848217-00-5
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5mg $54 In-stock
10mg $90 In-stock
25mg $156 In-stock
50mg $240 In-stock
100mg $370 In-stock
250mg $630 In-stock
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Cat. No. : HY-114025
M.Wt: 316.79
Formula: C16H17ClN4O
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 848217-00-5 :

H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. IC50 & Target: IC50: 19 nM (H4R)[1]. In Vitro: H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM[1]. In Vivo: H4 Receptor antagonist 1 indicates that metabolic stability in rat microsomes is very low with only 1% parent compound remaining after 10 min incubation[1].

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