Gefitinib N-oxide


CAS No. : 847949-51-3

847949-51-3
Price and Availability of CAS No. : 847949-51-3
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Cat. No. : HY-100636
M.Wt: 462.90
Formula: C22H24ClFN4O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 847949-51-3 :

Gefitinib N-oxide is the N-oxide derivative of Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2]. IC50 & Target: IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells)[1]

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