RTI-118


CAS No. : 847554-50-1

847554-50-1
Price and Availability of CAS No. : 847554-50-1
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5mg $280 In-stock
10mg $460 In-stock
25mg $850 In-stock
50mg $1350 In-stock
100mg $2150 In-stock
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Cat. No. : HY-111308
M.Wt: 448.56
Formula: C26H32N4O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 847554-50-1 :

RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration[1]. In Vitro:RTI-118 (109 nM) has a reduction in antagonist potency at the NPS 107I variant[2]. In Vivo:RTI-118 (5-30 mg/kg, intraperitoneal injection; pre-30 minutes) is well tolerated in rats with no significant outward signs of aversion, sedation or toxicity, it also produces a dose-related decrease in food self-administration[1].

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