Isoastragaloside I
CAS No. : 84676-88-0
(Synonyms: Isoastragaloside-I)
| Size | Price | Stock |
|---|---|---|
| 1mg | $55 | In-stock |
| 5mg | $160 | In-stock |
| 10mg | $255 | In-stock |
| 25mg | $480 | In-stock |
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| Cat. No. : | HY-N0887 |
| M.Wt: | 869.04 |
| Formula: | C45H72O16 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production. IC50 value: Target: Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.
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