Itraconazole solution
CAS No. : 84625-61-6
(Synonyms: R51211 solution)
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| Cat. No. : | HY-FL17514 |
| M.Wt: | 705.63 |
| Formula: | C35H38Cl2N8O4 |
| Purity: | >98 % |
| Solubility: |
Itraconazole solution is mainly composed of Itraconazole (HY-17514). Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor[1][2][3][4].
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