Mitoquinol
CAS No. : 845959-55-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $135 | In-stock |
| 10mg | $215 | In-stock |
| 25mg | $425 | In-stock |
| 50mg | $680 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-124410 |
| M.Wt: | 680.83 |
| Formula: | C38H49O7PS |
| Purity: | >98 % |
| Solubility: |
Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs[1][2][3]. In Vitro:Mitoquinol (150-500 nM; 30 min-18 h) reduces the oxygen consumption rate associated with ATP production (IC50: 189 nM), increases mitochondrial proton leak, basal oxygen consumption rate, superoxide anion and H2O2 production, and enhances glycolysis in bovine aortic endothelial cells[1]. In Vivo:Mitoquinol (40 mg/d; oral administration; twice daily; 3 days) exerts ameliorative effects against heat stress in crossbred barrows[2].
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