AP23464


CAS No. : 845895-51-4

845895-51-4
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Cat. No. : HY-10638
M.Wt: 475.52
Formula: C26H30N5O2P
Purity: >98 %
Solubility:
Introduction of 845895-51-4 :

AP23464 is an ATP-based inhibitor for Kit, that inhibits the phosphorylation of Kit wildtype and mutants, with IC50 of 5-85 nM. AP23464 inhibits the proliferation of Kit mutated cells (IC50 is 3-20 nM), arrests the cell cycle at G0/G1 phase, and induces apoptosis in Kit mutated cells[1].

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