ICI 162846
CAS No. : 84545-30-2
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|---|---|---|
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| 5mg | $121 | Get quote |
| 10mg | $175 | Get quote |
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| Cat. No. : | HY-101234 |
| M.Wt: | 306.29 |
| Formula: | C11H17F3N6O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
ICI 162846 is an orally active antagonist of H2 receptor. ICI 162846 inhibits acid production accompanied by an increase in the secretion of histamine in chronic duodenal ulcer (CDU) models. ICI 162846 is effective in preventing CDU[1][2]. In Vivo:ICI 162846 (10 mg/kg, p.o., twice daily for 5 days) reduces the incidence of CDU and inhibits acid production accompanied by an increase in the secretion of histamine in induced CDU models of CFLP mice[2].
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