GSK163090
CAS No. : 844903-58-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $260 | In-stock |
| 50mg | $660 | In-stock |
| 100mg | $980 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14348 |
| M.Wt: | 415.53 |
| Formula: | C25H29N5O |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
GSK163090 is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4, 8.5 and 9.7, respectively. GSK163090 inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK163090 has antidepressant and anxiolytic activities[1]. In Vivo:GSK163090 (compound 36) shows clear dose-dependent inhibition of the 8-OH-DPAT-induced hyperlocomotor activity (hLMA) in male Sprague-Dawley rats, with ED50 values ranging from 0.03 to 1 mg/kg[1].
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