IFN alpha-IFNAR-IN-1
CAS No. : 844882-93-5
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| Cat. No. : | HY-12836 |
| M.Wt: | 279.40 |
| Formula: | C18H17NS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM)[1].
In Vitro:IFN alpha-IFNAR-IN-1 (compound 1) (18 μM; 24 h) specifically inhibits MVA-induced IFN-a responses by BMpDCs[1].
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