Bithionol (sulfoxide)
CAS No. : 844-26-8
| Size | Price | Stock |
|---|---|---|
| 50mg | $40 | In-stock |
| 100mg | $60 | In-stock |
| 500mg | $130 | In-stock |
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| Cat. No. : | HY-17592A |
| M.Wt: | 372.05 |
| Formula: | C12H6Cl4O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 233.33 mg/mL (ultrasonic) |
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection[1][2][5].
In Vitro:Bithionol sulfoxide (0.1-10 mg/mL, 72 h) shows toxicity to Neoparamoeba spp parasites in sea water[1].
Bithionol sulfoxide (1-1000 μg/plate) exhibits mutagenic activity, in the absence of metabolic activation, in strains TA98 and TA100 (in Salmonella/mammalian microsome test)[5].
In Vivo:Bithionol sulfoxide (oral administration) shows LD50 values of 1000-5000 mg/kg (mice) and about 5000 mg/kg (rats), and increased serum AST at high doses (5000-100 mg/kg)[3].
Bithionol sulfoxide (80 and 90 mg/kg, oral administration) is effective against natural rumen fluke infections in dairy cattle[4].
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