α-Arbutin


CAS No. : 84380-01-8

(Synonyms: 4-Hydroxyphenyl α-D-glucopyranoside)

84380-01-8
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Cat. No. : HY-N3002
M.Wt: 272.25
Formula: C12H16O7
Purity: >98 %
Solubility: H2O : 125 mg/mL (ultrasonic)
Introduction of 84380-01-8 :

α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes[1][2][3][4]. In Vitro:α-Arbutin (0.5-2 mM, 1-10 days) significantly inhibits melanin synthesis at noncytotoxic concentrations and reduces cellular tyrosinase activity in HMV-II cells[3].
α-Arbutin (125 and 250 mg/tissue, 13 days) decreases melanin synthesis without affecting cell viability in the three-dimensional cultured skin model[3].

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