| Size | Price | Stock |
|---|---|---|
| 5mg | $420 | In-stock |
| 10mg | $720 | In-stock |
| 25mg | $1120 | In-stock |
| 50mg | $1500 | In-stock |
| 100mg | $2000 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-10249A |
| M.Wt: | 357.37 |
| Formula: | C16H19N7O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C) |
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1]. In Vitro: The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion[1]. In Vivo: Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus[1].
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