Fmoc-N-Me-Val-OH


CAS No. : 84000-11-3

84000-11-3
Price and Availability of CAS No. : 84000-11-3
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Cat. No. : HY-I1112
M.Wt: 353.42
Formula: C21H23NO4
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 84000-11-3 :

Fmoc-N-Me-Val-OH is an N-methylated valine derivative with an Fmoc protecting group, serving as a building block for solid-phase synthesis of coibamide A[1]. In Vitro:Fmoc-N-Me-Val-OH is an Fmoc-protected N-methylated amino acid derivative used in solid-phase peptide synthesis (SPPS). Its α-amino group is protected by a base-labile Fmoc group, while N-methylation reduces hydrogen bonding interactions and conformational flexibility. This compound is commonly used to enhance the metabolic stability, protease degradation resistance, and membrane permeability of peptides.

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