Toxoflavin
CAS No. : 84-82-2
(Synonyms: Xanthothricin; Toxoflavine; PKF-118-310)
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $590 | In-stock |
| 100mg | $890 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100760 |
| M.Wt: | 193.16 |
| Formula: | C7H7N5O2 |
| Purity: | >98 % |
| Solubility: | H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 25 mg/mL (ultrasonic) |
Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity[1][2].
IC50 & Target:TCF4/β-catenin[1], KDM4A[2]
In Vitro:Toxoflavin (Xanthothricin) exhibits dose-dependent cytotoxicity against the 3 hepatoma cell lines, and with IC50s of 0.66 μM, 0.36 μM and 0.98 μM for Hep40 cells, HepG2 cells and Huh7 cells respectively[1].
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