Minoxidil sulfate
CAS No. : 83701-22-8
| Size | Price | Stock |
|---|---|---|
| 25mg | $90 | In-stock |
| 50mg | $150 | In-stock |
| 100mg | $240 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-B1445 |
| M.Wt: | 289.31 |
| Formula: | C9H15N5O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic) |
Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo[1][3]. IC50 & Target:IC50: K channel[2] In Vitro: Minoxidil sulfate (1-100 μM; 2 hours) significantly reduces the permeability of bloode-brain tumor barrier (BTB) in a monolayer of RBMEC in a time-dependent manner, additionally,the effects of MS on transendothelial electrical resistance (TEER) is Transendothelial electrical resistance (TEER) at 2 h with high concentration[2].Minoxidil sulfate (0-100 μM; 0-4 hours) increases the RhoA activation in brain tumor tissue by 1 h and the highest level appears at 2 h, it also significantly induces transient PKB phosphorylation at Ser-473, without affecting total PKB levels. Addiotionally, LY294002 partly prevents the phosphorylation of PKB induced by MS[2].
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