7-Chloro-4-(piperazin-1-yl)quinoline


CAS No. : 837-52-5

837-52-5
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Cat. No. : HY-W020111
M.Wt: 247.73
Formula: C13H14ClN3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 837-52-5 :

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively[1].

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