7-Chloro-4-(piperazin-1-yl)quinoline
CAS No. : 837-52-5
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| Cat. No. : | HY-W020111 |
| M.Wt: | 247.73 |
| Formula: | C13H14ClN3 |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C) |
7-Chloro-4-(piperazin-1-yl) quinoline is a quinoline-class synthetic intermediate that is used in organic synthesis-related research[1][2].
In Vitro:7-Chloro-4-(piperazin-1-yl) quinoline serves as an intermediate in the synthesis of VEGFR-2 inhibitors, such as compound 57, which exhibits cytotoxicity against MCF-7 cells and inhibits VEGFR-2 kinase with an IC50 of 1.38 µM[1].
7-Chloro-4-(piperazin-1-yl) quinoline can serve as a pharmaceutical intermediate in the synthesis of nitroimidazole-7-chloroquinoline conjugates[2].
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