Naphazoline


CAS No. : 835-31-4

(Synonyms: Naphthazoline)

835-31-4
Price and Availability of CAS No. : 835-31-4
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5mg $50 In-stock
10mg $70 In-stock
25mg $115 In-stock
50mg $167 In-stock
100mg $248 In-stock
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Cat. No. : HY-111326
M.Wt: 210.27
Formula: C14H14N2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 835-31-4 :

Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research[1][2]. In Vivo: Naphazoline (0.2 mg/kg, 10 μl per eye; IP, once) reduces histamine or antigen-induced conjunctival vascular hyperpermeability in mice, and reduces conjunctivitis in mice via effects on inflammation, NGF and VEGF[1].

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