Voglibose
CAS No. : 83480-29-9
| Size | Price | Stock |
|---|---|---|
| 50mg | $84 | In-stock |
| 100mg | $125 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-B0025 |
| M.Wt: | 267.28 |
| Formula: | C10H21NO7 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 250 mg/mL (ultrasonic) |
Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis[1].
In Vitro: Voglibose (50 μM; 72 h) has no effect on SW480 and SW837 cells proliferation in both situation with 10 nM IGF-1 or not[1].
In Vivo: Voglibose (10 mg/kg; po for 15 weeks) has an inhibitory effect on the development of colorectal pre-neoplastic lesions in Azoxymethane (HY-111375)-induced diabetic and obese db/db mice model[1].
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