Sultamicillin (tosylate)
CAS No. : 83105-70-8
(Synonyms: Sultamicillin (tosilate))
| Size | Price | Stock |
|---|---|---|
| 500mg | $40 | In-stock |
| 1g | $70 | In-stock |
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| Cat. No. : | HY-N7111 |
| M.Wt: | 766.86 |
| Formula: | C32H38N4O12S3 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity[1].
In Vitro:Sultamicillin tosylate shows antibacterial activity against MRSA with a MIC value of 25 μg/mL[4].
In Vivo:Upon oral absorption, Sultamicillin tosylate is hydrolyzed to Sulbactam (HY-B0334) and Ampicillin (HY-B0522)[2].
Sultamicillin (oral gavage, every 12 h) tosylate combined with immunosuppression agent (eg: Mycophenolate mofetil (HY-B0199) and Methylprednisolone (HY-B0260)) markedly improves survival of experimental polymicrobial sepsis in mice, and enhances bacterial clearance[3].
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