(-)-Epigallocatechin-3-(3''-O-methyl) gallate
CAS No. : 83104-87-4
(Synonyms: (-)-EGCG-3''-O-ME)
| Size | Price | Stock |
|---|---|---|
| 1mg | $200 | In-stock |
| 5mg | $480 | In-stock |
| 10mg | $650 | In-stock |
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| Cat. No. : | HY-N2228 |
| M.Wt: | 472.40 |
| Formula: | C23H20O11 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product that can be isolated from the tea leaf, with strong antioxidative activity. (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells[1].
In Vitro:(-)-Epigallocatechin-3-(3''-O-methyl) gallate scavenges DPPH-derived radicals (IC50: 36.54 μM), and scavenges ABTS radicals (IC50: 2.59 μM)[2].
(-)-Epigallocatechin-3-(3''-O-methyl) gallate (12.5 μM, 30 min) scavenges intracellular ROS production in RAW264.7 cells[2].
(-)-Epigallocatechin-3-(3''-O-methyl) gallate (6.25 and 12 μM, 24-72 h) promotes cell proliferation in HaCaT cells[2].
(-)-Epigallocatechin-3-(3''-O-methyl) gallate (6.25 and 12 μM, 12 h) increased HO-1 expression in HaCaT cells treated with 250 μM H2O2[2].
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