Rotenone
CAS No. : 83-79-4
| Size | Price | Stock |
|---|---|---|
| 500mg | $50 | In-stock |
| 1g | $60 | In-stock |
| 5g | $108 | In-stock |
| 10g | $173 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-B1756 |
| M.Wt: | 394.42 |
| Formula: | C23H22O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.
In Vitro:Mitogen Activated Protein Kinase (MAPK), Toll-like receptor, Wnt, and Ras signaling pathways are intensively involved in the effect of rotenone on the ENS[2].
In Vivo:Note:
Please do not refer to only one article to determine the experimental conditions. It is recommended to determine the optimal experimental conditions (animal strain, age, dosage, frequency and cycle, detection time and indicators, etc.) through preliminary experiments before the formal experiment.
Rotenone can be used to create Parkinson's disease models.
Administration: 30 mg/kg in 12 mL/kg • po • once daily for 28 days
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