Deoxycholic acid
CAS No. : 83-44-3
(Synonyms: Cholanoic acid; Desoxycholic acid)
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
| 500mg | $70 | In-stock |
| 1g | $84 | In-stock |
| 5g | $130 | In-stock |
| 10g | $160 | In-stock |
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| Cat. No. : | HY-N0593 |
| M.Wt: | 392.57 |
| Formula: | C24H40O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C) |
Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2].
IC50 & Target:TGR5[1]
In Vitro: Deoxycholic acid (DCA) (100 μM) induces the production of gastric cancer cell line MGC803 resistant to acidified bile acids and enhances their survival and proliferation activity under bile acid stress[2].
Deoxycholic acid (DCA) (100 μM)-induced resistant cells shows altered morphology, significantly elevated telomerase activity, better cell viability and reduces apoptosis compared to normal MGC803 cells[2].
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