Phenindione


CAS No. : 83-12-5

(Synonyms: Rectadione)

83-12-5
Price and Availability of CAS No. : 83-12-5
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Cat. No. : HY-B0325
M.Wt: 222.24
Formula: C15H10O2
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL;H2O : 0.67 mg/mL (ultrasonic)
Introduction of 83-12-5 :

Phenindione is an anticoagulant which functions as a Vitamin K antagonist. Target: Others Phenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1].

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