MALAT1-IN-1


CAS No. : 827327-28-6

827327-28-6
Price and Availability of CAS No. : 827327-28-6
Size Price Stock
5mg $50 In-stock
10mg $85 In-stock
25mg $185 In-stock
50mg $300 In-stock
100mg $510 In-stock
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Cat. No. : HY-115579
M.Wt: 323.39
Formula: C19H21N3O2
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 827327-28-6 :

MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1]. IC50 & Target:Malat1[1] In Vitro:MALAT1-IN-1 (Compound 5) (1 μM, 7 days) reduces Malat1 levels and mammary tumor organoid branching in an organoid model of mammary cancer derived from MMTV-PyMT luminal B tumors in mice[1].
MALAT1-IN-1 (0.5 and 1 μM) inhibits downstream targets of Malat1 (krt16) and increases csn2 in MMTV-PyMT tumor organoids[1].

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