| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $85 | In-stock |
| 25mg | $185 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $510 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-115579 |
| M.Wt: | 323.39 |
| Formula: | C19H21N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1].
IC50 & Target:Malat1[1]
In Vitro:MALAT1-IN-1 (Compound 5) (1 μM, 7 days) reduces Malat1 levels and mammary tumor organoid branching in an organoid model of mammary cancer derived from MMTV-PyMT luminal B tumors in mice[1].
MALAT1-IN-1 (0.5 and 1 μM) inhibits downstream targets of Malat1 (krt16) and increases csn2 in MMTV-PyMT tumor organoids[1].
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