Verubulin
CAS No. : 827031-83-4
(Synonyms: MPC 6827)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $135 | In-stock |
| 50mg | $475 | In-stock |
| 100mg | $760 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14907 |
| M.Wt: | 279.34 |
| Formula: | C17H17N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Verubulin (MPC-6827) is a highly potent and broad-spectrum microtubule blocker. Verubulin has antitumor activity against breast cancer, melanoma, and ovarian cancer. Verubulin can be used in non-small cell lung cancer research[1][2][3].
IC50 & Target:Microtubule[1]
In Vitro:Verubulin (10 nM; 1-3 h) rapidly disrupts microtubule formation in human A549 non-small-cell lung carcinoma cells[2].
Verubulin inhibits the growth of MCF-7 cells with an IC50 value of 2.1 nM[2].
In Vivo:Verubulin (7.5 mg/kg; i.v.; once or 1 mg/kg; i.v.; 5 days) induces tumor growth inhibition in B16 mouse melanoma model[3].
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