5J-4
CAS No. : 827001-82-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $361 | Get quote |
| 10mg | $560 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-110216 |
| M.Wt: | 312.35 |
| Formula: | C16H12N2O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation[1].
In Vivo: 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt[1].
5J-4 (2 mg/kg; i.p.; every alternate day for 30 days) reduces the symptoms and delayed the onset of EAE[1].
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